The main road starts at a junction four kilometers west of Trinidad. The road to Topos de Collantes is about fifteen kilometers and is amazingly steep. It is paved well by Cuban standards.
The road from Cienfuegos through La Sierrita to San Blas is good, and quite scenic. Near San Blas is a cliff with stalactites. Somewhere between San Blas and Buenos Aires, near the village of Matagua, the pavement ends. Locals say the road is impassable after this, unless you have a Jeep. This road goes to Topos de Collantes, and has a turnoff that goes to El Nicho. This road goes through the highest mountains and might be a good mountain bike ride. Be aware that much of the area is military zone, so don't go hiking off the road, or take too many pictures.